They kept everything in the (fictional) family.
Emily VanCamp and Chris Pratt
Ian Somerhalder and Maggie Grace
Katherine Heigl and Jason Behr
Matthew Broderick and Jennifer Gray
Maureen McCormick and Barry Williams
Shannen Doherty and Jason Priestley
Lauren Graham and Peter Krause
Michael C. Hall and Jennifer Carpenter
Evan Rachel Wood and Shane West
Amy Poehler and Will Arnett
Susan Dey and David Cassidy
Kirstie Alley and Parker Stevenson
Drew Barrymore and David Arquette
And finally, Tom Hanks and Rita Wilson
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